Set in the year 2030, three decades after an event known as the Broadcast, the story follows Pax, an ex-con, outcast, and con artist who is also an Anomal, a person with superhuman powers fueled by disinformation. Pax takes on a job to transport a package across a divided America, but it proves far too dangerous to manage alone. The fanatical Puritans are in pursuit, the authoritarian Justice stands in the way, and Pax is four months pregnant. To survive, Pax gathers a motley crew of misfits, each with their own strange powers, and together they must overcome the obstacles between them and their destination through manipulation, subterfuge, and force, all while Pax tries to escape a troubled past.