Null Keeper is a sci-fi lair-building and management game in the tradition of dungeon-management games, set inside an asteroid in deep space. Players designate tunnels to be dug, claim the floor space and build rooms such as vaults, habitats, BioSynth labs and combat simulators, and summon creatures through Warp Rifts. Increasingly well-equipped Vanguard raids target the base's Void Core, and losing it ends the run, so players lay out defenses and choke points to protect it. A fully voiced, sarcastic AI named MALACHAR narrates and comments on the player's decisions.